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【轉(zhuǎn)載】再談表觀遺傳學(xué)

 成靖 2015-06-01
   

(1)

表觀(后成,漸成)遺傳學(xué)是關(guān)于我們的基因能被我們的行為、吃入或吸入的物質(zhì)而打開或關(guān)閉的研究。這項(xiàng)科學(xué)很新穎,它的意義受到熱烈地爭論。盡管約10年以前人類基因組工程預(yù)料測繪一個(gè)人的基因?qū)?huì)告訴你所有你需要知道的關(guān)于你的身體將如何行為,但在本質(zhì)上,但這種確信近年來已經(jīng)削弱了,其原因之一可能就是表觀遺傳學(xué),基因如何受到行為的鼓勵(lì)。這也是為什么你或曾想過我們分析帶有完全相同基因的人,隨著他們年齡增長,他們看上去會(huì)越來越不相像,并且容易患上不同的疾病。

——《文獻(xiàn)檔案》/《基因興奮劑使用》,BBC 2014/1/14

(17s57s)

Epigenetics is the study of how our genes can be stitched on or off or turned up or down like a dimmer switch on a light by what we do, or eat, or inhale. The science is new, and its implications hotly contested. But essentially it argues that while, maybe ten years ago, the Human Genome Project predicted that mapping a person’s genes would tell you all you need to know about how their body will behave; such certainty has ebbed away in recent years. And one of the reasons could be epigenetics, how genes are encouraged to behave, which is why once you’ve thought we examine people who may share exactly the same genes but who look less similar as they age and susceptible to different diseases.

-- Documentary Archive / Gene Doping, BBC 2014/1/14

(2)

表觀遺傳學(xué)在改變神經(jīng)元如何相互連接。表觀遺傳學(xué)研究的是非核酸分子?;蚴怯蒁NA組成的。你還有非DNA的分子也坐在這DNA上……但關(guān)鍵是它們不是DNA,基本上它們就如同圖書館的圖書管理人員。如果說DNA是書的話,表觀遺傳分子就是圖書管理員。有一位圖書管理員在你每次來圖書館時(shí)想讓一本書被閱讀,他或她說:來讀這本書,來讀這本書,來讀這本書。對(duì)于他或她不喜歡的書,放到櫥柜里,不讓它們出去。

——《演說家論壇》/《丹尼爾談青少年的腦與心理》,KUOW公共電臺(tái) 2013/1/24

(36m27s)

Epigenetics is changing how neurons connect to each other. Epigenetics are non-nucleic acid molecules. Genes are made of DNA. And you have non-DNA molecules sitting on the DNA… But the point is that they are not DNA, but they are like, basically they are like librarians in library. If the DNA is, are the books, then the epigenetic molecules are the librarians. And there is a librarian that wants one book to be read every time you come to the library. He or she says here read this one. Here read this one. Here read this one. And here is one he or she doesn’t like, put them in a closet and don’t let them out.

-- Speakers Forum / Inside the Teenage Brain with Daniel Siegel, KUOW Public Radio 2014/1/24

 

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